Solutions & Capabilities

Preclinical drug discovery is a high-stakes journey—filled with scientific complexity, biological uncertainty, and costly setbacks. At Canhitt, we turn those challenges into opportunities. Our cutting-edge platform blends AI-powered prediction, deep biological insights, and precision experimentation to streamline every step from hit to lead. Whether you're facing tough targets, toxicity surprises, or mechanistic black boxes, we help you navigate the maze with speed, clarity, and confidence. Let’s accelerate your next breakthrough—smarter, faster, and with fewer detours.

Graphene Quantum Dots

Targeted Chimeras (PROTACs)

Hit Discovery

Our hit discovery services leverage proprietary structure- and ligand-based drug design workflows that seamlessly integrate physics-based modeling with cutting-edge artificial intelligence. By combining molecular docking, dynamics simulations, and quantum mechanics with AI-driven scoring and virtual screening, we rapidly identify high-quality hit compounds with improved precision and diversity. Our platform accelerates early-stage discovery while ensuring data-driven decisions for downstream optimization.

Chemical Synthesis

Our chemical synthesis services offer end-to-end support for a broad range of molecules, including small molecules, peptides, quantum dots, oligonucleotides, siRNAs, PROTACs, and fluorophores. Whether you need milligram-scale custom compounds or complex multifunctional molecules, our experienced team and state-of-the-art facilities ensure high-quality, reliable synthesis tailored to your needs. Don’t see your molecule of interest on the list? Reach out to us—we’re always open to new challenges and will work with you to find a solution.

Lead Optimization

Got a lead compound? We're here to help you optimize it for potency, selectivity, ADMET properties, and developability. Our lead optimization services combine structure-based design, predictive modeling, and iterative synthesis to fine-tune your hits into high-quality candidates. Using advanced QSAR techniques and AI-driven analytics, we uncover key structure–activity relationships (SAR) and guide intelligent modifications that accelerate your path to the clinic.

Discover What Drives Biology at the Atomic Level

Get to the root of biological function with our deep-dive molecular mechanism services. We combine the power of structural biology, molecular dynamics, and AI-driven analytics to reveal how proteins move, interact, and drive critical cellular processes. From decoding enzyme catalysis to mapping drug resistance, we help you visualize the invisible and transform complex molecular behavior into actionable insights—fueling smarter design and better decisions in therapeutics and beyond.

Precision Bioassays, Built for Discovery

Unlock the full potential of your discovery pipeline with our custom bioassay development services. From fluorescent and luminescence-based assays to FRET, enzyme kinetics, target engagement, and cell-based functional assays, we design and optimize assays that are both sensitive and scalable. Whether you're working with small molecules, peptides, PROTACs, or siRNAs, we tailor each assay to your biology and screening needs—ensuring robust, high-throughput-ready platforms that deliver meaningful, decision-driving data. If you have a target, we’ll help you measure what matters.

Redesigning Proteins, Redefining Possibilities

Our protein engineering services go beyond optimization—we reimagine what proteins can do. Using a powerful blend of structure-guided design, machine learning, and directed evolution, we tailor enzymes and binding proteins for enhanced stability, function, and novel activity. Whether you're building a next-generation therapeutic, a resilient industrial biocatalyst, or a custom scaffold, we design with purpose and precision. From concept to engineered construct, we help you turn complex protein challenges into transformative solutions.

Know Your Molecule-Before It Hits the Clinic

Our DMPK (Drug Metabolism and Pharmacokinetics) services give you the insights you need to confidently move your molecule forward. From absorption and bioavailability to metabolic stability, clearance, and tissue distribution, we provide comprehensive in vitro and in vivo studies tailored to your drug’s journey through the body. Powered by cutting-edge analytics and expert interpretation, our DMPK workflows help you identify liabilities early, optimize lead compounds, and de-risk development. Because a great drug isn’t just potent—it’s predictable.